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Phenylpiracetam (cas (77472-70-9) has the function to improve memory

Date : 2016/8/31 13:50:23

Phenylpiracetam (cas 77472-70-9) has the function to improve memory, cholinergic receptor excited medicine also has the function to improve the memory. Cholinergic receptors can be divided into a toadstool alkali type (M) and nicotinic (N) cholinergic two kinds big. M1 receptor excited medicine is one of the ideal drug to improve memory decline, mainly are accounted for, merrill lynch, Myra Kang Meilin merrill lynch, sand, etc. But because these drugs gastrointestinal reactions and for M1 receptor specificity recognition is not enough, did not become a specific people expected. Targacept company Ispronicline (AZD3480) is 4 - beta 2 subtype selective nicotinic receptor alpha excited medicine, pre-clinical tests show that its nerve protective effect, can significantly improve the consciousness of the function in patients with AD. Varenicline is also a kind of nicotinic receptors part excited medicine, it can not only cure the nicotine addiction, but also can improve the cognitive ability of patients, has finished Ⅱ as AD drugs clinical trials.

ACTS on the brain of choline neurotransmitter receptors drugs are another drug to improve memory besides phenylpiracetam(cas 77472-70-9). With the deepening of the research work, represented by glutamate (Glu) of excitatory amino acids in the role of memory has become a research focus, especially Glu receptor subtype of N - methyl - aspartate (NMDA) receptor is cherished, its representative drug for dollars just amide and yellow skin. Just is first used in the treatment of moderately severe AD dollars noncompetitive NMDA receptor antagonist medicine, basic no bad reaction. A relation between double-blind, placebo-controlled clinical trial in patients with AD, according to us just has good tolerance. Yellow skin amide is yellow skin of rutaceae plants to extract the effective ingredient, the study found that the yellow skin amide have a role to improve memory and cognitive function. In addition, the neurotransmitter serotonin (5 - HT) can also affect cognitive function. Five - HT1A, 5 - HT4, 5 - HT6 memory can be used as drug development targets, the variety of 5 - HT6 receptor antagonist agents into clinical trials.