News Introduction

Study of 1,4-dimethoxybenzene(cas 150-78-7)

Date : 2016/8/22 11:45:47

Preparation 1,4-dimethoxybenzene(cas 150-78-7): Strongly acidic cation exchange resin as catalyst, p-benzoquinone as the promoters studied hydroquinone and methyl ether synthesis reaction hydroxyanisole process conditions. The results show that at a temperature of 60 ℃, methanol than hydroquinone substance is 10: 1, hydroquinone and benzoquinone mass ratio of 3.3: 1, hydroquinone and catalyst mass ratio of 1.5: 1 Optimization under the reaction conditions of 4h, hydroquinone conversion was 76.0%, p-hydroxy anisole selectivity was 98.4%.

In the past 20 years, and their derivatives with calixarene unique structure and excellent performance attracted wide interest in the majority of scientific researchers. Calixarene compounds are widely used in many fields, such as gas adsorption, nano-pipes, catalysts, DNA identification and fullerene chemistry. With the continuous development of calixarene chemistry, many new calixarene constantly being synthesized, widely used in the field of supramolecular chemistry. These new calixarene include calixpyrrole thiosulfate calixarene, oxa with cup aromatics. Compared with many meta calixarene reported in the literature regarding its position like - learn column aromatics are few. In 2008, Ogoshi first reported two kinds of such compounds. They study Lewis acid-catalyzed terephthalic dimethyl ether paraformaldehyde and the reaction was first discovered in the para methylene bridged benzene pentamer named aromatic methoxy pillars; dealkylation get through BBr3 full aromatic hydroxy column shows the good performance of the main object. Unfortunately, the low yield of aromatics column. Based on the study of benzyl ethers of acid-catalyzed reactions, we have discovered a new method of synthesis of aromatic hydrocarbon column. The process is of simple raw materials, the reaction time is short, easy to operate, high yield. By influence the reaction of different solvents, catalysts, reaction temperature, reaction time, etc., to find the best reaction conditions: methylene chloride as solvent, toluene sulfonic acid as a catalyst; alkoxy were selected to different substrates and side chain ether substrate to study the effect on the reaction; synthesized a series of derivatives of aromatic hydrocarbon column; by analyzing the crystal structure found column aromatics acetonitrile hydration pack. First synthesis of aromatic hydrocarbon column column column aromatics aromatics 27b and 210b, and a detailed structural characterization. Column aromatics by ceric ammonium nitrate oxidation of a new type of electron-deficient aromatic hydrocarbon column - column quinone.

The results showed that: (1) With the increase of substrate carbon chain alkyl ether oxygen, hindered the increase, the reaction time is prolonged aromatics column, column aromatics yield decreased slightly column aromatics yield increased , but the total column near quantitative yield aromatics; (2) with the increase of substrate benzyl ether side chain carbon chain, steric hindrance is increased, the reaction time was prolonged column aromatics, the reaction conditions are more severe (requires refluxing) column significantly decreased the yield of aromatics yield increased aromatics column, the column and the total yield of aromatics is also high. Aromatic hydrocarbon synthesis reaction column, pentamer highest yield. Improved synthetic methods for the preparation of dialkoxy column with a benzene aromatics. In this method, methylene chloride as solvent, toluene sulfonic acid as catalyst dialkoxy benzene and paraformaldehyde prepared by reacting an aromatic hydrocarbon column, the yield is higher. Synthesized 13 ~ 5a, 13 ~ 5b, 13 ~ 5c, 13 ~ 5d and 14 ~ 5a, 14 ~ 5b, 14 ~ 5c, 14 ~ 5d eight asymmetrical column aromatics, and were characterized. By analyzing the crystal structure of 13 ~ 5b- 13 ~ 5d verified the column aromatic solvent molecules hydration pack. Asymmetric high overall yield aromatics column, three of which are inconsistent alkyl toward asymmetric column aromatic product yields close to yield alkyl toward consistent asymmetrical product is significantly lower than the other three isomers. Asymmetric synthesis of aromatic hydrocarbon column, the selection of methyl and ethyl carbon chain substrates, found only give a product, show asymmetric column aromatic ring may occur twist. By studying the reaction intermediates, reaction phenomenon, combined with analysis of relevant literature, the mechanism proposed by column aromatics synthesis reaction is a radical reaction by cations. A preliminary study of the alkoxy aromatics column and molecular recognition properties butylamine hydrochloride class, and column 9 to 5 with pyridine quinone, 1,4-dimethoxybenzene(cas 150-78-7) and p-phenylenediamine molecular recognition performance.