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Effect of tianeptine sodium(CAS 30123-17-2) and psychological treatment for depression in patients with neurological rehabilitation after stroke

Date : 2016/8/9 11:14:41

Comparison of conventional therapy, psychotherapy, and psychological impact of tianeptine sodium(CAS 30123-17-2) treatment combined tianeptine four different methods for neurological rehabilitation of patients with depression after stroke. Methods: 120 cases of stroke depression were randomly divided into four groups, namely the control group (A), the psychotherapy group (B), tianeptine treatment group (C) and psychological treatment and tianeptine treatment group ( D), respectively, before and after treatment were depression severity score and activities of daily living (activity of daily living scale, ADLS) Hamilton Rating depression scale (HAMA), and then analyze the results. Results: The treatment group after 12 weeks there is a statistically significant difference to relieve depression and improve the level of daily living.
Tianeptine sodium(CAS 30123-17-2) combination Deanxit Depression Clinical contrast observation and fluoxetine treatment:
Study tianeptine and Deanxit combined treatment of depression. Methods: 159 patients were randomly divided into two groups tianeptine and Deanxit combined group 81 cases (tianeptine 37.5mg / d,. Deanxit 2 / d), fluoxetine 78 cases (20m ~ d). Hamilton depression scale (HAMD24) to assess the clinical effects, adverse reactions using scale (TESS) to assess the clinical safety outcomes: thiophene total Deanxit tianeptine and fluoxetine group and the combination group rates were 85.2% and 64.1% significant difference (P <0.01) the combined group the onset time of 1 week, fluoxetine group. 4 weeks combined group HAMD reduction rate in the treatment of sub-1,2,4,6 weeks higher than fluoxetine group, the difference was significant (P <0.01). Side effects of fluoxetine combined group difference was not significant (is 0.05) Conclusion: tianeptine sodium(CAS 30123-17-2) and Deanxit combination is effective in treating depression, rapid onset of methods, safety and compliance is good.