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Extraction 3,4-dihydroxybenzaldehyde(cas 139-85-5) on purification process

Date : 2016/8/23 11:56:09

3,4-Dihydroxybenzaldehyde(cas 139-85-5) is a component of traditional Chinese medicine. Chinese medicine extraction and purification process is the key to the mass transfer of Chinese medicine, including the extraction, separation, concentration, drying and other technology sectors. Extraction process of Chinese medicine is to re-acquire chemicals group and purification, which includes the target component extraction, homes and composition changes in the design of traditional Chinese medicine extraction and purification scheme, should have the following understanding:

(1) Chinese medicine herbs, traditional effect is all reflected the combined effect of the active ingredients of traditional Chinese medicine, Chinese medicine called "quality systems";

(2) extraction and purification of active ingredients must be designed, ineffective ingredients(such as 3,4-dihydroxybenzaldehyde(cas 139-85-5)), toxic components, basic judgment of unknown composition;
(3) extraction and purification process design is based on medicinal ingredient contained in the difference between their physical and chemical properties, including molecular size, melting point, boiling point, polarity, solubility, volatility, pH, chromatographic behavior;
(4) single-fried and fried together different effect exists between the composition of solubilization, antagonize, decomposition, precipitation, complex, compound and other physical and chemical changes;
(5) Chinese medicine prescription and its traditional use is an important basis for the extraction and purification process selection;

(6) extraction and purification process is the key factor in traditional Chinese medicine and then mass formed.

Technical rules for the formulation efficacy of the drug have a role in the following three aspects:

(1) choose the type of active ingredients, and the number of existing forms;
(2) control the release rate of the active ingredient(3,4-dihydroxybenzaldehyde(cas 139-85-5) is one of the active ingredient);
(3) direct control of the rate of absorption of the drug. Crushing constitutes preparation process, extraction, separation, concentration, drying and preparation methods, process conditions, etc., it must be determined through continuous experimentation. Wherein the low temperature extraction, supercritical extraction, microcapsules, microspheres, liposomes technology, centrifugal separation, ultrafiltration technology and other advanced technology to Chinese medicine is the key to raising the level of Chinese medicine. Thus, formulation and reform process specification should draw medicine modern science and technology as much as possible.